|
Symbol Name ID |
Ctla4
cytotoxic T-lymphocyte-associated protein 4 MGI:88556 |
| Darker colors indicate more annotations |
| Human Phenotypes | Diffuse alveolar hemorrhage |
Localized pulmonary hemorrhage |
Sinusitis |
Pleural effusion |
Chylothorax |
Pneumonia |
Asthma |
Recurrent respiratory infections |
Recurrent sinopulmonary infections |
Bronchoconstriction |
Rhinorrhea |
Dyspnea |
Abnormal lung morphology |
Hemosiderin-laden macrophages in bronchoalveolar fluid |
Elevated bronchoalveolar lavage fluid neutrophil proportion |
Abnormal pleura morphology |
Pleuritis |
Pneumothorax |
Pulmonary fibrosis |
Emphysema |
Pulmonary infiltrates |
Hemoptysis |
Bronchiectasis |
Tracheal stenosis |
Subglottic stenosis |
Airway hyperresponsiveness |
Chronic pulmonary obstruction |
Upper airway obstruction |
Cough |
Respiratory insufficiency |
| Disease(s) Associated with CTLA4 | ||||||||||||||||||||||||||||||
| asthma | ||||||||||||||||||||||||||||||
| atopic dermatitis | ||||||||||||||||||||||||||||||
| chronic obstructive pulmonary disease | ||||||||||||||||||||||||||||||
| graft-versus-host disease | ||||||||||||||||||||||||||||||
| granulomatosis with polyangiitis | ||||||||||||||||||||||||||||||
| immunoglobulin alpha deficiency | ||||||||||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||||||||||
| sarcoidosis | ||||||||||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | lung inflammation |
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| Availability | Mouse Genotype | |
| Ctla4tm1Shr/Ctla4tm1Shr | ||
| Ctla4tm1Saka/Ctla4tm1Saka Foxp3tm1(cre)Saka/Y (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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